Quote Originally Posted by amalone View Post
I wonder if you all would be willing to resurrect this conversation with an update. I am one of the few people with DF508 and R334W. I would love to hear if anyone with that mutation has gotten a chance to try Kalydeco since you all last posted.

I am fairly mild in my Cf presentation. My FEV1 hovers around 75% of predicted. I am pancreatic sufficient and have manageable sinus issues. A couple docs have danced around sinus surgery but decided against it. Presently my primary method of controlling my pulmonary function is Hypertonic Saline and regular running.
I guess I am very lucky and I pray I stay that way. My FEV is 111-114. I have colitis which I am managing with diet and L-Glutamine. Never took Kalydeco b/c I am not sick. Why are people taking it?