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anonymous
02-13-2006, 10:16 PM
I have been asked to participate in a trial with Mannitol. Must be new to Canada because I have not heard of it yet.
Wondering if anyone is using it and how it works


Bob 31 w/CF

anonymous
02-13-2006, 10:16 PM
I have been asked to participate in a trial with Mannitol. Must be new to Canada because I have not heard of it yet.
Wondering if anyone is using it and how it works


Bob 31 w/CF

anonymous
02-13-2006, 10:29 PM
Its a diuretic...
Do you inhale it in the study?
I did a study some 10 or 15 years ago, where I inhaled amiloride (also a diuretic), but havent heard a thing about it since.
Hopefully its more promising than amiloride.
-jd

anonymous
02-13-2006, 10:29 PM
Its a diuretic...
Do you inhale it in the study?
I did a study some 10 or 15 years ago, where I inhaled amiloride (also a diuretic), but havent heard a thing about it since.
Hopefully its more promising than amiloride.
-jd

JennifersHope
02-13-2006, 10:33 PM
My guess is that you would be inhaling it, any other way can cause serious electrolyte imbalances..I believe It would work the same way as hytertonic saline, because they are similiar. We give in in the emergency room to help reduce swelling in the brain, since it is hypertonic it pulls the fluid out of the brain,,,, I imagine the idea would be to pull the mucus out of the lungs.... This is off the top of my head.. so I may be wrong.. and someone feel free to correct me..


Jennifer

JennifersHope
02-13-2006, 10:33 PM
My guess is that you would be inhaling it, any other way can cause serious electrolyte imbalances..I believe It would work the same way as hytertonic saline, because they are similiar. We give in in the emergency room to help reduce swelling in the brain, since it is hypertonic it pulls the fluid out of the brain,,,, I imagine the idea would be to pull the mucus out of the lungs.... This is off the top of my head.. so I may be wrong.. and someone feel free to correct me..


Jennifer

anonymous
02-13-2006, 11:44 PM
The Mannitol study is comparing its benefits to those of HS. Yes, it would be inhaled. There was a mention of this in the Boston Globe a few weeks ago, and a friend also emailed me this link:

<a target=new class=ftalternatingbarlinklarge href="http://erj.ersjournals.com/cgi/content/abstract/14/3/678
">http://erj.ersjournals.com/cgi/content/abstract/14/3/678
</a>
Hope it helps.

anonymous
02-13-2006, 11:44 PM
The Mannitol study is comparing its benefits to those of HS. Yes, it would be inhaled. There was a mention of this in the Boston Globe a few weeks ago, and a friend also emailed me this link:

<a target=new class=ftalternatingbarlinklarge href="http://erj.ersjournals.com/cgi/content/abstract/14/3/678
">http://erj.ersjournals.com/cgi/content/abstract/14/3/678
</a>
Hope it helps.

anonymous
02-13-2006, 11:46 PM
Mannitol is a hypertonic solution, so it pulls water by osmosis out of the vessels which hydrates the sputum...thats the idea...
but that is what they tried to do w/ inhaled amiloride years ago, and said it didn't do much. I think hypertonic saline (the so-called sea water or whatever) must work better, and cheaper

anonymous
02-13-2006, 11:46 PM
Mannitol is a hypertonic solution, so it pulls water by osmosis out of the vessels which hydrates the sputum...thats the idea...
but that is what they tried to do w/ inhaled amiloride years ago, and said it didn't do much. I think hypertonic saline (the so-called sea water or whatever) must work better, and cheaper

anonymous
02-13-2006, 11:47 PM
Jennifer,
where are you a nurse? an RN?
I want to get my RN

anonymous
02-13-2006, 11:47 PM
Jennifer,
where are you a nurse? an RN?
I want to get my RN